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New method development for PK and immunogenicity for large molecule

Lambda has successfully developed and validated bioanalytical methods to support pharmacokinetics measurement and immunogenicity assessment of Romiplostim. Romiplostim is a fusion protein analog of Thrombopoietin and is indicated for treatment of chronic idiopathic (immune) thrombocytopenic purpura (ITP). The pharmacokinetic measurement assay is a sandwich ELISA based...

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13 November
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  |   Panomics   |   No comment

Analytical Arsenal for Biosimilarity Assessment

Biosimilars Debut: Emerging Opportunities in Biopharma Industry   Biosimilars are biologics containing the same active ingredient as the originator. Biosimilars have the exact amino acid composition and highly similar glycosylation patterns overlapping with the originator reference product. Biosimilar protein characterization studies involve extensive structural characterization and include...

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31 March
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  |   Panomics   |   No comment

Analytical Arsenal for Biosimilarity Assessment

Focus Area: Capillary Electrophoresis and Mass Spectrometry   Capillary electrophoresis (CE) is a powerful analytical technique for the separation of charged analytes, offering uniquely high analyte resolution. The advantages of CE include ease of automation, small sample volume requirement, robust separation efficiency and short duration of analysis.   CE...

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07 March
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